Dissident AIDS Database

Antibody testsNegative AIDS casesNon ICLAfrica
For debate. AIDS surveillance in Africa: a reappraisal of case definitions
 De Cock KM, Selik RM, Soro B, Gayle H, Colebunders RL
  2215 out of 4383 (50.0%) African AIDS patients from Abidjan, Ivory Coast, Lusaka, Zambia, and Kinshasa, Zaire, were HIV-antibody negative.
  Br. Med. J. 303, 1185-1188, 19911991
Tuberculosis and HIV infection.
 Taelman, H., et al.
  2215 out of 4383 (50.0%) African AIDS patients from Abidjan, Ivory Coast, Lusaka, Zambia, and Kinshasa, Zaire, were HIV-antibody negative.
  Br. Med. J. 302, 1206, 19911991
Clinically diagnosed AIDS cases without evident association with HIV type 1 and 2 infections in Ghana
 Hishida O, Ido E, Igarashi T, Hayami M, Miyazaki A, Ayisi NK, Osei-Kwasi M
  Another study using antibody tests and supplementary PCR tests for HIV reports 135 (59%) HIV-free AIDS patients from Ghana out of 227 suffering from weight loss, diarrhea, chronic fever, tuberculosis, and neurological diseases.
  Lancet 340, 971-972, 19921992
Quantitative bacillary response to treatment in HIV-associated pulmonary tuberculosis
 Brindle RJ, Nunn PP, Githui W, Allen BW, Gathua S, Waiyaki P
  Only 37 (30%) of a group of 122 African tuberculosis patients with "AIDS" were HIV-positive. "The response to treatment was similar, but with HIV-positive patients more likely to become culture negative by 28 days. The differences that exist between HIV-positive and HIV-negative patients are minor, and standard regimens are at least as effective in HIV-positive patients in the first month of treatment"
  Am. Rev. Respir. Dis. 147, 958-961, 19931993
Evaluation of the WHO clinical case definition for AIDS in Uganda.
 Widy-Wirski R, Berkley S, Downing R, Okware S, Recine U, Mugerwa R, Lwegaba A, Sempala S.
  Documents 116 HIV-negatives among 424 African patients
  JAMA 260, 3286-3289, 19881988
Prevalence of antibodies to lymphadenopathy-associated retrovirus in African patients with AIDS.
 Brun-Vezinet, F. Rouzioux, C. Montagnier, L. Chamaret, S. Gruest, J. Barre-Sinoussi, F. Geroldi, D. Chermann, J.C. McCormick, J. Mitchell, S. Piot, P. Taelman, H. Mirlangu, K.B. Wobin, O. Mbendi, N. Mazebo, P. Kalambayi, K. Bridts, C. Desmyter, J. Feinsod, F.M. & Quinn, T.C.
  In 1984, sera from 37 out of the 38 patients who were diagnosed in Kinshasha in October 1984 were tested for HIV antibodies by Montagnier and 19 of his associates including researchers from the CDC. The sera were tested by ELISA and followed by a RIPA test similar to the Western blot. The latter was considered positive if a p24 band was present (since 1987, nobody in the world with the possible exception of Montagnier, considers the p24 band proof of HIV infection, not even in Africa). Thirty two (88%) patients were positive by both tests.
  Science 1984 226, 453-4561984
Surveillance for AIDS in a central African city.
 Mann, J.M. Francis, H. Quinn, T. Asila, P.K. Bosenge, N. Nzilambi, N. Bila, K. Tamfum, M. Ruti, K. Piot, P. McCormick, J. & Curran, J.W.
  During an 8 month period the research groups had "565 suspected AIDS cases" in Kinshasa (Zaire). Of the 565 patients, 332 (58.8%) were found to have a positive HIV antibody test, and because of this were considered to be confirmed AIDS cases. "A specimen was considered positive for antibody to HTLV-III if it was repeatedly reactive on two separate ELISA assays ...
  Journal of the American Medical Association 1986 255, 3255-3259.1986
Seroepidemiological studies of HTVL-III antibody prevalence among selected groups of heterosexual Africans.
 Clumeck, N. Robert-Guroff, M. Van De Perre, P. Jennings, A. Sibomana, J. Demol, P. Cran, S. & Gallo, R.C.
  Gallo and his associates also tested Africans for HIV antibodies. Of 53 patients with AIDS, "46 (87%) tested positive...67 (80%) of 84 prostitutes [without any clinical symptoms] and five (12.5%) of 40 and eight (15.5%) of 51 healthy controls and blood donors, respectively", also tested positive. Sera which had one positive ELISA were considered as proof for HIV infection. Sera which had a borderline ELISA were further tested with the WB. In the WB, "serum samples possessing reactivity to HTLV-III p41 and/or p24 were scored positive.
  Journal of the American Medical Association 1985 254, 2599-2602.1985
Distribution of CD4+ T-lymphocytes levels in patients with clinical symptoms of AIDS in three west African countries.
 Adu-Sarkodie Y, Sangare A, d'Almeida OA, Kanmogne GD.
  "Selected patients had clinical AIDS, according to the WHO clinical definition of AIDS in Africa. In patients with clinical AIDS but without HIV antibodies, the mean CD4+ cell level was 807/microliter; with 4% below 200/microliter and 14.7% below 400/microliter..."
  J Clin Virol 1998 Dec;11(3):173-811998
Low prevalence of human T-lymphotrophic virus type I (HTLV-I) in HIV-positive patients in Kenya.
 Songok EM, Tukei PM, Libondo D, Gichogo A, Oogo SA
  913 patients with "AIDS": 71% test HIV-negative
  J Acquir Immune Defic Syndr. 1994 Aug;7(8):876-71994
Idiopathic CD4+ T-lymphocyte depletion in a west African population.
 Djomand, G., L. Diaby, J. M. N'Gbichi, D. Coulibaly, A. Kadio, A. Yapi, J. M. Kanga, E. Boateng, K. Diallo, L. Kestens, and et al.
  "In the absence of HIV infection, CD4+ T-lymphocytopenia is uncommon ( 1%) in West African asymptomatic individuals but is more frequent in those with tuberculosis (4%) and hospitalized patients (10%). CD4+ T-lymphocytopenia in HIV-negative individuals was not associated with wasting syndrome or increased mortality. There was no evidence for frequent, clinically relevant immune deficiency other than that associated with HIV infection"
  Aids. 8(6):843-7. 1994.1994