Dissident AIDS Database

CD4+ countsInconsistent surrogate markerStandardsNormal range
Screening of blood donors for idiopathic CD4+ T-lymphocytopenia.
 Busch MP, Valinsky JE, Paglieroni T, Prince HE, Crutcher GJ, Gjerset GF, Operskalski EA, Charlebois E, Bianco C, Holland PV, et al
  “To evaluate the prevalence and significance of low CD4+ values among blood donors, CD4+ data on 2030 blood donors who were negative for antibody to human immunodeficiency virus type 1 (HIV-1) were compiled. In this report, we present data on the prevalence of CD4+ T-lymphocytopenia [low CD4 cell counts in HIV-negative people] among healthy, volunteer, anti-HIV-1-negative blood donors...Five (0.25%) of 2030 index donations had a CD4+ count <300 cells per microliter or a CD4+ percentage <20%. On follow-up, all five donors had immunologic findings within normal ranges, lacked HIV risk factors, and tested negative for HIV types 1 and 2 and human T-lymphotropic virus type I and II infections by antibody and polymerase chain reaction assays. Four of five donors reported transient illness shortly after their low CD4+ count donations.” [personal comments : Assuming that there are 270 millions 1) middle-aged 2) healthy americans 3) outside AIDS risk groups 4) hiv negative and 5) not submitted to any known form of immunosuppressive therapy, there should be (using the figure about blood donors of 0,25%) about 675 000 such cases in the USA (of course not all falling with AIDS diseases). That is about the estimated number of hiv +. Assuming that there are quite a few hiv negative people belonging to Aids risk group, or old, or seriously ill that have such a condition (T cell lymphocytopenia : from 2% to 10% according to other studies), the number of T cell lymphocytopenia cases is actually higher. In the same time, the number of hiv + immunosuppressed is obviously lower than 650 000. It is therefore very likely that the number of immunosuppressed hiv - people (not because of immuno-suppressive therapy) is by far more important that the number of hiv + immunosuppressed people right now in the States]
  Transfusion. 1994;34(3):192.1994
Revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adults.
 No author
  “[Table 1 in this paper shows that 95% of CD4 cell counts in perfectly healthy people are between 40-1680 per microliter or 290-2070, depending on the mathematical model used. Note that the CDC 1993 definition of AIDS includes people with a count below 200, within the normal limits for one model, and not far off for the other].”
  MMWR. 1992;41(RR-17):1-17.1992