Dissident AIDS Database
|Glucocorticosteroid therapy: Mechanisms of Action and Clinical Considerations.|| ||Fauci, A.S., Dale, D.C., and Balow, J.E.
| ||“we have reviewed many aspects of the host defenses that are altered by corticosteroids, and the combined effects of these changes must be considered in trying to understand the relation between corticosteroids and infections. Since the defect with corticosteroids is broad, it is not surprising that many types of infections seem to occur more often in patients treated with corticosteroids. Of the bacterial infections, staphylococcal and Gram-negative infections, as well as tuberculosis and Listeria infections, probably occur most often. Certain types of viral, fungal, and parasitic infections also occur often. Patients with lupus erythematous, rheumatoid arthritis, and renal transplant have more infection with steroid administration. Studies of bronchial aerosols showed that with higher doses of steroid in the aerosol, Candida infections of the larynx and pharynx occurred more often”.|
| ||Annals of Internal Medicine 84: 304-15, 1976||1976|