Dissident AIDS Database

Co-factorsGlucocorticoidsTreatment of AIDS risk groupsTreatment of PCP
Treatment and prophylaxis of Pneumocystis carinii pneumonia.
 Castro M.
  "...Trimethoprim-sulfamethoxazole remains the agent of choice for treatment of severe P. carinii pneumonia. Pentamidine, trimethoprim-dapsone, atovaquone, and other regimens are useful in selected clinical situations. Adjunctive corticosteroids are indicated in patients with acquired immune deficiency syndrome and P. carinii pneumonia who have moderate to severe P. carinii pneumonia...
  Semin Respir Infect. 1998 Dec;13(4):296-3031998
Immunosuppressive Drugs and Corticosteroids for HIV Infection
 Loftus Rick
  "Corticosteroid drugs are analogs of natural hormones, made by the adrenal glands, that have anti-inflammatory properties. These drugs are used as short-term treatments for a host of AIDS-related conditions, such as neuropathy, esophageal ulcers, various skin rashes and thrombocytopenia. They are combined with other drugs to treat AIDS-related KS, acute Pneumocystis carinii pneumonia and tuberculosis and to reduce the increased intracranial pressure due to toxoplasmosis or CNS lymphoma."
  GMHC Treatment Issues - Vol. 9, No. 12 - December 19951995
Corticosteroid Utilization and Outcomes in HIV Associated Pneumocystis carinii Pneumonia: Three-fold Higher Mortality Among Severely Ill Patients When Corticosteroids Given by CDC Guidelines.
 McIlraith T et al.
  “Among severely ill patients, mortality was 3-fold higher when corticosteroids were given according to CDC guidelines. Our findings suggest that that the utility of adjunctive corticosteroids in severe PCP needs to be revisited.”
  6th Conf on Retroviruses and Opportunistic Infections. 1999.1999