Dissident AIDS Database

Co-factorsMalnutritionAIDS symptomsOIs
Synergism of nutrition, infection, and immunity: an overview.
 Scrimshaw NS, SanGiovanni JP
  "Infections, no matter how mild, have adverse effects on nutritional status. The significance of these effects depends on the previous nutritional status of the individual, the nature and duration of the infection, and the diet during the recovery period [all of these factors are often adversely affected in people diagnosed HIV-positive]. Conversely, almost any nutrient deficiency, if sufficiently severe, will impair resistance to infection."
  Am J Clin Nutr 1997 Aug;66(2):464S-477S1997
Fatal infections in protein-calorie malnourished children with thymolymphatic atrophy.
 Purtilo DT, Connor DH.
  The clinicopathological features of 25 children who died with protein-calorie malnutrition were studied. All but four subjects were found at necropsy to have nutritional thymectomy and all but 3 died of infectious diseases. The infectious agents were chiefly intracellular micro-organisms including miliary tuberculosis, Herpes simplex, varicella, measles, Pneumocystis carinii, and Plasmodium falciparum. Staphylococcal infections, salmonellosis, shigellosis, strongyloidiasis, and hookworm were other significant infectious agents. Nutritionally acquired defective immunity, especially cell-mediated immunity, probably permitted these infectious agents to multiply and to disseminate widely.
  J Infect Dis. 1995 Feb;171(2):502-41995