Dissident AIDS Database

Co-factorsMalnutritionImmuno-deficiencyBabies (fetal malnutrition)
Fetal malnutrition and postnatal immunocompetence.
 Chandra RK.
  There is growing scientific data showing that many chronic diseases of adulthood have their origin at “in utero programming”. This includes several immunological disturbances. Therefore, it appears that whatever happens during embryonic and fetal times will be remembered by cells, tissues, organs, and systems throughout a lifetime.
  Am J Dis Child 1975b; 129: 450-454.1975
Interactions between early nutrition and the immune system
 Chandra RK.
  There is growing scientific data showing that many chronic diseases of adulthood have their origin at “in utero programming”. This includes several immunological disturbances. Therefore, it appears that whatever happens during embryonic and fetal times will be remembered by cells, tissues, organs, and systems throughout a lifetime.
  The childhood environment and adult disease. Barker DJL, Whelan J., Siba Foundation Symposium # 156. London: Wiley; 1991: 77-88.1991
Prenatal undernutrition is associated with reduced immune function in adolescence.
 McDade TW et al.
  There is growing scientific data showing that many chronic diseases of adulthood have their origin at “in utero programming”. This includes several immunological disturbances. Therefore, it appears that whatever happens during embryonic and fetal times will be remembered by cells, tissues, organs, and systems throughout a lifetime.
  FASEB 2000; 14: A792 (abs.).  2000
Prenatal undernutrition, postnatal environments, and antibody response to vaccination in adolescence.
 McDade TW et al.
  There is growing scientific data showing that many chronic diseases of adulthood have their origin at “in utero programming”. This includes several immunological disturbances. Therefore, it appears that whatever happens during embryonic and fetal times will be remembered by cells, tissues, organs, and systems throughout a lifetime.
  Am J Clin Nutr 2001a; 74: 543-548.2001
Antibody formation in first and second generation ofspring of nutritional deprived rats.
 Chandra RK.
  “Murine models have documented impairments in immunity after maternal undernutrition that last through adulthood and into the next generation, despite ad libitum feeding of both F1 and F2 generations”
  Science 1975c; 190: 289-290.1975
Gestational zinc deprivation in mice: persistence of immunodeficiency for three generations.
 Beach RS et al.
  In mice, deprivation of zinc during pregnancy causes immunodeficiency that can last at least for three generations
  Science 1982; 281: 469-4711982
Prenatal undernutrition and postnatal growth are associated with adolescent thymic function.
 McDade TW et al.
  There is growing scientific data showing that many chronic diseases of adulthood have their origin at “in utero programming”. This includes several immunological disturbances. Therefore, it appears that whatever happens during embryonic and fetal times will be remembered by cells, tissues, organs, and systems throughout a lifetime.
  J Nutr 2001b; 131: 1225-1231.2001
Defective immunocompetence in foetal undernutrition.
 Moscatelli P et al.
  There is growing scientific data showing that many chronic diseases of adulthood have their origin at “in utero programming”. This includes several immunological disturbances. Therefore, it appears that whatever happens during embryonic and fetal times will be remembered by cells, tissues, organs, and systems throughout a lifetime.
  Helv Paediatr Act 1976; 31: 241-247.1976
Prenatal or early postnatal events predict infectious deaths in young adulthood in rural Africa.
 Moore SE et al.
  “Research in Gambia associated season of birth with infectious disease mortality after the age of 15 years, suggesting an association between prenatal undernutrition, immune function, and adult vulnerability to infectious disease”
  Int J Epidemiol 1999; 28: 1088-1095.1999
Season of birth predicts mortality in rural Gambia.
 Moore SE et al.
  “Research in Gambia associated season of birth with infectious disease mortality after the age of 15 years, suggesting an association between prenatal undernutrition, immune function, and adult vulnerability to infectious disease”
  Nature 1997; 338: 434.1997