Dissident AIDS Database

Co-factorsMultiple infectionsHomosexualsSyphilis
http://www.cbc.ca/ideas/features/Aids/index.html
 Jones Colman
  In the late 70's / early 80's, years of the "gay liberation", an outbreak of syphilis infections took place in the homosexual communities of Europe and USA cities. This epidemic (in 1981, the CDC estimated there were about 325 000 cases of undiagnosed & untreated syphilis in the US, 2/3 of them distributed among gay men according to many reports in the field) was greatly under-reported, as a vast majority of cases went undiagnosed for the following reasons : 1) the symptoms of a new infection may be inexistent, painless, unspecific, invisible and short-lived, 2) there is a heavy social stigma attached to syphilis, preventing patients from reporting the disease, 3) contact tracing is impossible in a context of very promiscuous sexual life styles, 4) the existing serological screening tests are unreliable, particularly in the absence of active symptomatic infections. The absence of diagnosis, and thus treatment, resulted in a multitude of chronic syphilis infections with serious implications : if the syphilis germ has not been properly treated the first time, the immune system can lose memory and become unable to fight the disease due to the loss of antibodies, and the next infections may be symptomless. This situation may lead to genetic changes severely deterious to the immune system by preventing cytokine-secreting cells from producing the appropriate levels of these chemicals (like IL-6 and IL-10). As the classical symptoms of syphilis are direct consequences of immunologic well-being (auto-immune process involving destruction of connective tissue), they rarely ever occur in AIDS patients whose immune systems are no longer able to fight the syphilis infection. The latter are then more prone to develop a late latent form of syphilis whose symptoms are unclear and which often masquerade as other diseases. Syphilis is then an indirect cause of other diseases and syphilitics are known to suffer from excess mortality and opportunistic infections (pneumonia, reactivated TB, cancer) independently of the classical late symptoms of syphilis. It is thus quite likely that the diagnosis of syphilis have been globally overlooked in the pathology of aids, hiv being blamed for about everything in hiv + people. Since the beginning of the safe sex era, syphilis (and AIDS) incidence has naturally gone down but cases start to grow again, especially in Eastern Europe and Russia, as people take less precautions. (Scythes J, Jones Colman, Syphilis: the "elephant in the room" of AIDS?" posted to the British Medical Journal website, April 30, 2002 as an online Rapid Response to the March 16 BMJ editorial "Shame: the elephant in the room", by Frank Davidoff, http://bmj.com/cgi/eletters/324/7338/623#21759, Scythes J, Jones Colman, Response to Minority Statement and Recommendations to the Government of South Africa", the point-by point May 15, 2000 response on the minority statement by dissident scientists issued after the first meeting of the South African President Thabo Mbeki's HIV/AIDS panel, http://aidsmyth.addr.com/news/000516syphilis.htm, Scythes J, Jones Colman, "Deja Vu: Aids In Historical Perspective", the 2-part series on CBC Radio's "Ideas" broadcast January 9 & 10, 1996, http://www.cbc.ca/ideas/Aids, Scythes J, Jones Colman, scientific abstracts and papers by Scythes and his colleagues, presented at international AIDS and STD conferences, http://www.cbc.ca/ideas/features/Aids/scythes.html, Scythes J, Jones Colman, The Cause of AIDS: Fact and Speculation", the Rogers Cable 10 1993 television documentary series, http://colman.net/aids/video.html, McKenna, Joan et al, Medical Hypotheses, vol. 21 (1986), p. 421-430, Unmasking AIDS: Chemical Immunosuppression and Seronegative Syphilis, Coulter, Harris L. Berkeley, 2nd edition (revised and enlarged) New Delhi: B. Jain Publishers (P) Ltd., 1990, AIDS and Syphilis: The Hidden Link, Caiazza, Stephen S., Quantum Medicine, vol. 1, no. 1 (1988), p. 117-127, Chronic Spirochetal Infection and the Pathogenesis of AIDS, Mitchell, Robert Ben. Austin, Texas: Banned Books, 1988 (excerpted in New York Native, January 30 through March 13, 1989). Syphilis as AIDS, Scythes J, Jones Colman, Implications of the Recent Lyme Culture Technique for the Diagnosis of Syphilis, poster presented at the 12 th International Conference on Lyme Disease and Other Spirochetal and Tick-Borne Disorders, New York City, April 9 & 10, 1999, http://www.cbc.ca/ideas/features/Aids/lyme.html, Scythes J, Jones Colman, Syphilis, HIV and AIDS: new approaches for the 21st century, the communication Scythes posted December 21, 1998 to several STD/AIDS-related Internet newsgroups and mailing lists, http://www.cbc.ca/ideas/features/Aids/syphilis21.html, Scythes J, Jones Colman, Spectrum of Cellular Immune Responses to the Human Immunodeficiency Viruses and the Human Treponematoses, an abstract  accepted for a co-plenary presentation in the oral sessions at the VenSouth '97 IUVDT HIV/STD World Congress, Melbourne, Australia, June 1997, http://www.cbc.ca/ideas/features/Aids/melbourn.html)
  11
Syphilis in HTLV-III infected male homosexuals.
 Sindrup JH et al.
  A history of having had syphilis in the past is one of the best predictor of subsequent "HIV" infection (or activation) and progression to the AIDS syndrome
  AIDS Res 2(4): 285-8 (1986)1986
Trends in sexual behaviour and risk factors for HIV infection among homosexual men, 1984-7
 Evans B et al.
  A history of having had syphilis in the past is one of the best predictor of subsequent "HIV" infection (or activation) and progression to the AIDS syndrome
  Br Med J 298: 215-18 (1989)1989
No title
 Berger JR et al.
  A history of having had syphilis in the past is one of the best predictor of subsequent "HIV" infection (or activation) and progression to the AIDS syndrome
  Int Conf AIDS 5: 93 (1989) abstract no. M.A.P. 901989
No title
 Rose TP et al.
  A history of having had syphilis in the past is one of the best predictor of subsequent "HIV" infection (or activation) and progression to the AIDS syndrome
  Int Conf AIDS 5: 360 (1989) abstract no. W.B.P. 531989
Possible correlation between exposure to AIDS risk factors, clinical presentation in AIDS, and subsequent prognosis
 Messiah A et al.
  A history of having had syphilis in the past is one of the best predictor of subsequent "HIV" infection (or activation) and progression to the AIDS syndrome
  Eur J Epidemiol 5(3):336-42 (1989)1989
HIV-1 and pregnant women: associated factors, prevalence, estimate of incidence and role in fetal wastage in central Africa.
 Miotti PG et al.
  A history of having had syphilis in the past is one of the best predictor of subsequent "HIV" infection (or activation) and progression to the AIDS syndrome
  AIDS 4(8): 733-6 (1990)1990
Inpatient morbidity among HIV-infected male soldiers prior to their diagnosis of HIV infection
 Renzullo PO et al.
  A history of having had syphilis in the past is one of the best predictor of subsequent "HIV" infection (or activation) and progression to the AIDS syndrome
  Am J Public Health 81 (1991) 1280-12841991
No title
 Veugelers PJ, et al.
  A history of having had syphilis in the past is one of the best predictor of subsequent "HIV" infection (or activation) and progression to the AIDS syndrome
  8th Int Conf AIDS (1992), abstract no. 44861992
Characteristics of African-American college students with HIV/AIDS.
 Johnson, EH et al.
  A history of having had syphilis in the past is one of the best predictor of subsequent "HIV" infection (or activation) and progression to the AIDS syndrome
  J Natl Med Assoc 86(12): 931-40 (1994)1994
1
 Horvath I, et al.
  A history of having had syphilis in the past is one of the best predictor of subsequent "HIV" infection (or activation) and progression to the AIDS syndrome
  Sex Transm Dis 21 (1994) suppl S199, abstract 3211994
The homosexual transmission of HIV/AIDS in Mexico
 Izazola-Licea JA et al.
  A history of having had syphilis in the past is one of the best predictor of subsequent "HIV" infection (or activation) and progression to the AIDS syndrome
  Salud Publica Mex 37(6): 602-14 (1995)1995
Rates of and factors associated with self-reported prior HIV testing among adult medical patients in an inner city emergency department in the Bronx, New York City
 Shuter J et al.
  A history of having had syphilis in the past is one of the best predictor of subsequent "HIV" infection (or activation) and progression to the AIDS syndrome
  J Acquir Immune Defic Syndr Hum Retrovirol 14(1): 61-6 (1997)1997
Drug use and syphilis. Co-factors for HIV transmission among commercial sex workers in Guyana
 Persaud NE et al.
  A history of having had syphilis in the past is one of the best predictor of subsequent "HIV" infection (or activation) and progression to the AIDS syndrome
  West Indian Med J 48(2): 52-6 (1999)1999