Dissident AIDS Database

Co-factorsRecreational drugsCocaineDementia
Do alcohol and cocaine abuse alter the course of HIV-associated dementia complex?
 Tyor WR, Middaugh LD.
  "Although psychoactive drugs are commonly used by AIDS patients, it is unclear whether commonly abused drugs, such as cocaine and ethanol, affect the course of HIV-associated dementia (HADC). Epidemiological studies have resulted in conflicting conclusions as to what role, if any, abused drugs play in HADC. In this review we discuss the clinical and pathological evidence that cocaine and ethanol might exacerbate the detrimental effects of HIV infection on the brain... We conclude that abused drugs likely affect the course of HADC but that proof awaits an examination of their interactive effects in an appropriate in vivo system of retroviral encephalitis."
  J Leukoc Biol 1999 Apr;65(4):475-811999