Dissident AIDS Database

Co-factorsRecreational drugsGeneralGeneral
No title
 Rasnick David
  Non-drug abusing prostitutes have no higher risk of AIDS than other women. (AIDS: the second decade, report from the National Academy of Sciences USA,1990). The same is true for prostitutes in Germany, Zurich, Vienna, London, Paris, Pardenone, and Athens. (Klinische Wochenschrift 65: 287 (1987), Luthy et al.; Wiener Klinische Wochenschrift 98: 697 (1986), Kopp & Dangl-Erlach; Lancet ii: 1424 (1985), Brenky-Fandeux & Fribourg- Blanc; British Medical Journal 297: 1585 (1988), Day et al.; Scand J Infect Dis 21: 353 (1988), Hyams et al.)
Immune status of drug abusers.
 Fuchs D, Hausen A, Reibnegger G, Schonitzer D, Unterweger B, Blecha HG, Hengster P, Rossler H, Schulz T, Werner ER, et al.
  "This study followed 184 drug abusers. Examined in all of them were urinary neopterin levels, HBV, SGOT, and Luestest. Seventy-three percent of IV drug addicts showed elevated neopterin levels reflecting activated cellular immunity... Individuals using cocaine revealed higher neopterin levels than those not doing so... Thirty-eight of ninety-four parenteral drug addicts presented with anti-LAV/HTLV-III antibodies (ELISA + Western blot + IFT). Our data demonstrate an activated cellular immune status in parenteral drug addicts that cannot be attributed to LAV/HTLV-III infection in all cases. The development of AIDS seems to depend not only on the exposure to LAV/HTLV-III but also on activated cellular immunity, which is easily assessed by neopterin measurement." [Neopterin is a marker associated with cell-mediated immunity. It is produced in monocytes/macrophages primarily upon stimulation with interferon-gamma The levels of neopterin in body fluids are elevated in infections, autoimmune diseases, malignancies, allograft rejection, cardiac and renal failure, coronary artery disease and myocardial infarction. Neopterin measurements not only provide an insight into the present state of cell-mediated immune response but also allow monitoring and prognosis of disease progression.]
  Cancer Detect Prev Suppl 1987;1:535-411987