Dissident AIDS Database

HIV drugsAZT/PIsSide effectsChildren
Maternal and infant factors associated with failure to thrive in children with vertically transmitted Human Immunodeficiency Virus-1 infection: the prospective, P2C2 Human Immunodeficiency Virus Multicenter study.
 Miller TL et al.
  “FTT [failure to thrive among children of HIV-positive women] was associated with … any antiretroviral therapy by 3 months of age”
  Pediatrics. 2001 Dec;108(6):1287-96.2001
Natural history of somatic growth in infants born to women infected by human immunodeficiency virus.
 Moye J, Rich KC, Kalish LA, Sheon AR, Diaz C, Cooper ER, Pitt J, Handelsman E, for the Women and Infants Transmission Study Group.
  "In contrast with anecdotal clinical observations and other studies indicating that zidovudine favorably influences weight-growth rates, our analysis suggests the opposite...the result indicating no effect or a negative effect of zidovudine on growth should be interpreted with caution... However, our findings suggest that the widely held view that antiretroviral treatment improves growth in children with HIV disease needs further study."
  The Journal of Pediatrics 1996; 128: 58-671996