Dissident AIDS Database

NIAID paper : HIV causes AIDSDeveloped countriesDrug-AIDS connectionGay males : San Francisco study
Can Epidemiology Determine Whether Drugs or HIV Cause AIDS?
 Duesberg Peter
  (Ascher, M.S., Sheppard, H.W., Winkelstein Jr, W., Vittinghoff, E.: Does drug use cause AIDS? Nature 362, 103-104, 1992) During 8-year observation periods the San Francisco longitudinal survey of 812 homosexual men and 215 heterosexual controls observed that 215 out of 445 HIV positive drug users developed AIDS and that 39 HIV-free drug users did not develop AIDS. On the basis of these correlations the survey has concluded that HIV causes AIDS, and have rejected the hypothesis that recreational drugs and anti-HIV drugs, like AZT, cause AIDS. However => 1) the authors lacked drug-free AIDS cases, 2) the cumulative lifetime drug dose of the subjects (heavy or light, long or short term) was not determined (as drug toxicity is dosage dependent, no drug dose-AIDS response relationships could emerge), 3) self-reported drug use was not verified by any tests (this epidemiological honor system is certain to minimize drug-AIDS connections because people tend to forget and to deny socially unacceptable behavior like drug use. Indeed, denial is one of the first indications of all addictions), 4) AZT use was ignored. Contrary to the authors' conclusion, data of both surveys confirm the drug-AIDS hypothesis : 1) it is improbable that no AIDS defining disease occurred in 367 male drug users over 8 years since those diseases have always been described in drug addicts (100% of HIV-negative homosexual men had used nitrites and an unknown percentage had also used cocaine, amphetamines and other recreational drugs) which reflects the bias of either not diagnosing or not reporting AIDS-defining diseases in HIV-negatives, 2) since the numerous sexual contacts necessary to pick up HIV are frequently drug-promoted (particularly by nitrites), HIV antibody-positives are likely to have much more consumed drugs than HIV-negatives (proven by the facts that 72.9 % of the heavy drug users but only 50.9 % of the light users are HIV positive, that "heavy" drug users had 1.6 times as much AIDS and had 2 times as much Kaposi's sarcoma as "light" users, that 43% of AIDS victims had Kaposi's sarcoma -U.S. national average of 10%- and that 100 % of the AIDS patients had inhaled nitrites).
  AIDS-Forschung (AIFO), 12, pp. 627-635, December 19941993
The Drug-AIDS Hypothesis
 Duesberg Peter, Rasnick David
  (Ascher, M.S., Sheppard, H.W., Winkelstein Jr, W., Vittinghoff, E.: Does drug use cause AIDS? Nature 362, 103-104, 1992) The authors proudly display, on a blue colored background, a graph of "drug-free", HIV-positive AIDS patients losing their T cells over time. The graph demonstrates that the authors are clearly aware that a drug-free control group of HIV-positive AIDS patients is necessary to refute the drug hypothesis of AIDS, while at the same time supporting the orthodox view that HIV causes AIDS. However, the drug-free group reported by the authors proved to be an empty set, as no drug-free AIDS patients were recorded in the Nature commentary. Our independent analysis of the data base also failed to identify the missing group of drug-free AIDS patients. Despite our challenge in The Lancet, Genetica, and Science, to this date the authors have failed to come up with an explanation as to the origin of their drug-free group. The Nature commentary also omitted the fact that 73% of the HIV-positive AIDS patients were on AZT. However, in response to our challenge the authors acknowledged the AZT prescriptions 2 years later.
  Continuum Feb./March 19971997
HIV AS SURROGATE MARKER FOR DRUG USE: A RE-ANALYSIS OF THE SAN FRANCISCO MEN'S HEALTH STUDY
 Ellison BJ, Downey AB & Duesberg PH
  (Ascher, M.S., Sheppard, H.W., Winkelstein Jr, W., Vittinghoff, E.: Does drug use cause AIDS? Nature 362, 103-104, 1992) "Our analysis of drug use and morbidity data from a cohort of 1034 men yields the following results: 1) HIV infection is a strong indicator of drug use - HIV positive respondents reported an average lifetime dose of recreational drugs (excluding marijuana) 2.3 times higher than HIV negative respondents. 2) Homosexuality is a strong indicator of drug use - homosexual respondents reported an average lifetime dose 2.0 times higher than heterosexual respondents. 3) The incidence of AIDS-defining diseases was not limited to respondents infected with HIV (45 HIV-free patients with AIDS defining diseases that had been omitted from the original study), but was almost completely limited (98%) to respondents who reported using drugs. We also address a previous report (Ascher et al.) that was based on the same database and purported to show that HIV alone correlates with the development of AIDS. Specifically, we show that the relationship between HIV infection and CD4+ T Cell loss is weaker than reported by Ascher et al., and provides little evidence for causative relationship. These results support the hypothesis that long-term, habitual drug use can cause the conditions known as AIDS (independent of the presence of HIV), and refute the hypothesis that HIV alone causes these conditions independent of drug use."
  Genetica 95: 165-171, 19951995