Dissident AIDS Database

TreatmentAlternative treatmentsAntioxidants supplementationGeneral
Treatment of HTLV-III/LAV-infected patients with D-penicillamine.
 Schulof, R.S., Scheib, R.G., Parenti, D.M. et al.
  A reducing agent, D-penicillamine, previously used as an immunomodulator, and inhibitor of tumour promotion, may be useful in improving the immune response in HIV infected individuals and in preventing and treating AIDS.
  Drug Res. 1986, 36, (11),Nr 10, 1530-1535.1986
Fatty acids and plasma antioxidants in HIV-positive patients: correlation with nutritional and immunological status.
 Constants J et al.
  To investigate red blood cell (RBC) and plasma fatty acids (FA) in HIV-positive patients in relation to oxidative stress and nutritional or immunological status. FA, plasma selenium, vitamins A and E were measured in 95 patients divided into four groups according to CD4 cells. Poly- and di-unsaturated FA (PUFA, DUFA) decreased and saturated FA (SFA) increased in RBC in the patients below 400/mm3 and in plasma in the patients below 50/mm3. RBC SFA correlated to CD4 cells, PUFA to MDA. Unlike vitamin E, plasma vitamin A and selenium decreased in most groups. Plasma SFA and MUFA correlated negatively to selenium and PUFA and DUFA to vitamin E. No correlation was found between PUFA and nutritional markers. FA seem to be modified during HIV infection by oxidative stress and disease evolution, but not by denutrition.
  Clinical Biochemistry 1995; 28: 421-426.1995
Antioxidant micronutrients and immune function in HIV-1 infection
 Javier JJ et al.
  FASEB Proc 1990; 4A: 940-9451990
Antioxidant-micronutrients and HIV infection.
 Lacey CJ et al.
  We measured plasma levels of all the antioxidant-micronutrients in subjects with HIV infection and controls. Plasma levels of all the carotenoids, including lutein, cryptoxanthin, lycopene, alpha-carotene and beta-carotene as well as vitamins A, C and E and cholesterol were assayed in 35 subjects with HIV infection and 38 controls. We found a significant depletion of all the carotenoids (P < 0.001) and vitamin C (P < 0.01) and cholesterol (P < 0.001) but not vitamins A or E in HIV-infected subjects. Further analysis of the HIV-infected subjects revealed that plasma levels of 4 of the groups of carotenoids and cholesterol were correlated with CD4 count but that beta-carotene and vitamins A, C and E were not... an additional contribution to these deficiencies from malabsorption later in HIV disease cannot be ruled out.
  International J STD & AIDS 1996; 7: 485-489.1996
A prospective study of dietary intake and AIDS in HIV-seropositive homosexual men
 Abrams B et al.
  Increase intake of iron, vitamin E, and riboflavin significantly reduced the hazard for AIDS. In San Francisco, higher dietary intake of zinc, thiamine, niacin, and riboflavin were positively related to CD4 cell counts.
  J AIDS 1993; 6: 949-958.1993