Dissident AIDS Database

TreatmentAlternative treatmentsVitamins supplementationGeneral
Effects of vitamin E and C supplementation on oxidative stress and viral load in HIV-infected subjects.
 Allard JP et al.
  In a randomized, placebo-controlled, double-blind study in Canada, a significant reduction in viral load was achieved after 3 months of supplementation with large daily doses of vitamins C and E
  AIDS 1998; 12: 1653-1659.1998
Effects of micronutrient intake on survival in HIV-1 infection.
 Tang AM, Graham NMH, Saah AJ.
  In the MACS study, high dietary intake of vitamins B1, B2, B6, and niacin were associated with increased survival time of up to 1.3 years
  Am J Epidemiol 1996; 143: 1244-1256.1996
NUTRITIONAL THERAPY FOR THE TREATMENT AND PREVENTION OF AIDS, SCIENTIFIC BASES (Southern African Development Community (SADC), Health Ministers Meeting, Johannesburg, South Africa, January 20-21, 2003)
 Giraldo Roberto
  Beta-carotene is a provitamin A carotenoid that may enhance T-cell and B-cell immune function, possibly through conversion to vitamin A or by acting as an antioxidant. Daily supplementation of beta-carotene among elderly volunteers has led to an increase of T-lymphocytes and cells with interleukin-2 receptors. Furthermore, supplementation with beta-carotene or vitamin A is associated with enhanced cellular immunity in both humans and animals (Watson RR et al. Effect of beta-carotene on lymphocyte subpopulations in elderly humans: evidence for a dose-response relationship. Am J Clin Nutr 1991; 53: 90-94, Ross AC, Stephenson CB. Vitamin A and retinoids in antiviral responses. FASEB J 1996; 10: 979-985, Prabhala RH et al. The effects of 13-cis-retinoic acid and beta-carotene on cellular immunity in humans. Cancer 1997; 67: 1556-1560, Semba RD et al. Abnormal T-cell proportions in vitamin A-deficient children. Lancet 1993; 341: 5-8, Bendich A, Shapiro SS. Effects of beta-carotene and canthaxanthin on the immune responses of the rat. J Nutr 1996; 116: 2254-2262).
  Roberto Giraldo website2003
NUTRITIONAL THERAPY FOR THE TREATMENT AND PREVENTION OF AIDS, SCIENTIFIC BASES (Southern African Development Community (SADC), Health Ministers Meeting, Johannesburg, South Africa, January 20-21, 2003)
 Giraldo Roberto
  Supplementation with vitamin E in healthy elderly people significantly improved lymphocyte proliferation, IL-2 production, DTH, and response to T-cell-dependent vaccines, and reduced the incidence of infections (Meydani SN et al. Vitamin E supplementation enhances cell-mediated immunity in healthy elderly subjects. Am J Clin Nutr 1990; 52: 557-563, Meydani SN et al. Vitamin E supplementation enhances in vivo immune response in healthy elderly: a dose-response study. JAMA 1997; 277: 1380-1386.).
  Roberto Giraldo website2003
NUTRITIONAL THERAPY FOR THE TREATMENT AND PREVENTION OF AIDS, SCIENTIFIC BASES (Southern African Development Community (SADC), Health Ministers Meeting, Johannesburg, South Africa, January 20-21, 2003)
 Giraldo Roberto
  Vitamin C is an antioxidant that plays a role in immune responses and the formation of connective tissues. Proliferation of T and B lymphocytes increased following supplementation with vitamin C (Bendich A. Antioxidant vitamins and immune responses. In: Chandra RK, Alan R. Nutrition and immunology. New York: Liss., Inc., 1988: 125-147), and increased levels of vitamin C have been associated with lower rate of infections (Hemila H. vitamin C and infectious diseases. In: Pacler L, Fuchs J. Vitamin C in health and disease. New York: Marcel Dekker, 1997).
  Roberto Giraldo website2003
NUTRITIONAL THERAPY FOR THE TREATMENT AND PREVENTION OF AIDS, SCIENTIFIC BASES (Southern African Development Community (SADC), Health Ministers Meeting, Johannesburg, South Africa, January 20-21, 2003)
 Giraldo Roberto
  Several B-complex vitamins have roles in immune functions. Vitamin B6 deficiency in healthy elderly individuals significantly reduced the total number of lymphocytes, lymphocyte proliferation, and IL-2 production in response to mitogens; these defects were corrected following B6 repletion. Riboflavin deficiency has been shown to impair the ability to generate antibodies. Clinical studies show that individuals with low serum vitamin B12 had impaired neutrophil function, while animal studies indicate that vitamin B12 supplements are associated with enhanced humoral and cellular immune responses. (Meydani SN et al. Vitamin B-6 deficiency impairs interleukin-2 production and lymphocyte proliferation in elderly adults. Am J Clin Nutr 1991; 53: 1275-128, Bendich A, Cohen M. B vitamins: effects on specific and non-specific immune responses. In: Chandra RK, Alan R. Nutrition and immunology. New York: Liss, Inc., 1988: 101-123).
  Roberto Giraldo website2003