Dissident AIDS Database

TreatmentHiv drugs beneficial effectsAZT/PIsPCP
In Vitro Activity of Human Immunodeficiency Virus Protease Inhibitors against Pneumocystis carinii
 Atzori Chiara, Elena Angeli, Annalisa Mainini, Fiorenza Agostoni, Valeria Micheli, and Antonietta Cargnel
  Since 1996, the introduction of protease inhibitors (PIs) has led to a dramatic decrease of human immunodeficiency virus-related Pneumocystis carinii pneumonia... However, it is conceivable that PIs had other beneficial effects, including direct activity against Pneumocystis. These protease targets seemed to be affected in vitro by antiretroviral PIs. These data suggest intriguing implications for the possible antipneumocystis benefit of receiving indinavir, ritonavir, nelfinavir, or saquinavir during HAART.
  The Journal of Infectious Diseases, May 2000;181:1629-16342000