Dissident AIDS Database

Viral loadFalse viral loadCausesMalaria
The effect of Plasmodium falciparum malaria on HIV-1 RNA blood plasma concentration.
 Hoffman IF, Jere CS, Taylor TE, Munthali P, Dyer JR, Wirima JJ, Rogerson SJ, Kumwenda N, Eron JJ, Fiscus SA, Chakraborty H, Taha TE, Cohen MS, Molyneux ME
  "Malawian adults with symptomatic Plasmodium falciparum parasitemia (malaria group) -47-and asymptomatic, aparasitemic blood donors (control group) -42- were tested for HIV-1 antibodies to identify appropriate study groups. In both groups, blood plasma HIV-1 RNA viral concentrations were determined at enrollment and again at 1, 2 and 4 weeks. At enrollment blood plasma HIV-1 RNA concentrations were approximately sevenfold higher in patients with malaria than in blood donors (medians 15.1 x 10(4) and 2.24 x 10(4) copies/ml, respectively, P = 0.0001). HIV-1 blood viral burden is higher in patients with P. falciparum malaria than in controls and this viral burden can, in some patients, be partly reduced with antimalarial therapy."
  AIDS 1999 Mar 11;13(4):487-941999